You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. To help you decide whether Zetia is a good treatment choice for you, talk with your doctor. However, you may still experience muscle problems if you use Zetia alone. Other interactions can increase side effects or make them more severe. Taking Zetia with a statin drug may increase your risk of developing some mild or serious side effects. Last medically reviewed on September 18, 2021. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. People who may be at higher risk of this side effect include those who: Tell your doctor if any of the above apply to you before starting Zetia treatment. In studies, some people had to stop taking Zetia because of this side effect. All rights reserved. Zetia is available in a generic form called ezetimibe. Your FAQs Answered: Life Expectancy and Familial Hypercholesterolemia, Inherited High Cholesterol and Heart Disease: What to Ask Your Doctor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Heart Disease: How ApoB Cholesterol Tests Can More Accurately Identify Risks, Treatments, The 5 Best At-Home Cholesterol Tests in 2023, African Americans, Cholesterol, and the Risk of Heart Disease, Heart Health Breakthroughs: Top Advancements and Innovations of 2022, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, what dose of drug you were taking when you had the side effect, how soon after starting that dose you had the side effect, what your symptoms were from the side effect, what other medications you were also taking, any other information you feel is important, taking other medications, especially high dose statin drugs. No, clinical studies havent shown Zetia to affect blood pressure. Zetia isnt known to interact with grapefruit or any other foods. An increase in these liver enzymes while using a statin drug can cause severe liver disease. Mild side effects of Zetia when taken with a statin (another kind of cholesterol -lowering drug) may include: infection, such as a respiratory . Plant sterols are similar to cholesterol. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Read more about these alternatives to traditional statin, Having high cholesterol puts you at risk for a heart attack or stroke. Rhabdomyolysis can also occur with statin drugs, and you may need to take Zetia with a statin. Its a place where people with certain conditions can find support and connect with others. It can cause mild side effects and, less commonly, serious side effects. Dr. said Zetia was different and would not cause these side effects, so I agreed to try it. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. You should also look for supplements from reputable manufacturers. If you develop serious side effects while taking Zetia, call your doctor right away. Zetia and Lipitor have some similar side effects and others that vary. However, if the side effects last longer than . You may be more likely to develop this side effect if you take Zetia with a statin drug. Before taking Zetia, talk with your doctor about your health history. If you develop liver problems, you may be more likely to experience side effects with Zetia. In studies, muscle problems commonly occurred in adults and children who took Zetia with statin drugs. Forget HDL and LDL. Crestor contains the active drug rosuvastatin. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. The following lists contain some of the key side effects that may occur while taking Zetia. Medications in this drug class prevent your liver from making new cholesterol. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. The list below includes factors to consider. Phil Fischer, M.D., medical director of Mayo Clinic's children's hospital and a POTS specialist, led . Then theyll monitor whether the drug is working for you and whether you experience any side effects. In Zetia's clinical studies, these were some of the side effects that occurred more often: pain in the arms or legs. If you miss a dose of Zetia, you can take your missed dose as soon as you remember. The absence of symptoms doesn't necessarily mean that the cause of POTS is gone as well. Would a lower dose of Zetia help to reduce my risk of side effects? If you have questions about using Zetia and cholestyramine together, talk with your doctor. It can develop suddenly or maybe over time. Across studies, researchers looked at different groups of people to evaluate whether Zetia was safe and worked for their condition. Eating large meals can worsen hypotension in some individuals with dysautonomia (Mathias, 2000). After stopping Zetia treatment, their liver enzymes levels went back down. They may have suggestions depending on your weight and health goals. Zetia does not cause an increase or a decrease in blood pressure. Ways to reduce the symptoms. POTS is commonly associated with low levels of fluid. Do not use more Zetia than your doctor recommends. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Before trying something new, its common to look for written reviews about the experiences of others. But it may be a sign that your liver isnt working as well as it should. If you no longer need to take Zetia and have leftover medication, its important to dispose of it safely. However, 0.3% of people who took Zetia alone experienced joint pain so bothersome that they had to stop treatment. Drugs in this class prevent your small intestine from absorbing cholesterol. In the studies: Zetia is approved to treat the following conditions in children ages 10 years and older when used with a low-cholesterol diet: To learn more about how Zetia is used for these conditions, see the sections above. Some people experience mild side effects with Zetia. Zetia (ezetimibe) is a prescription drug that treats high cholesterol in adults and children. You likely wont notice Zetia working in your body. The actual price youll pay for any of these drugs depends on your insurance plan, your location, and the pharmacy you use. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. joint pain *. They can both be taken with or without food. Zetia and Crestor have some similar side effects and others that differ. But reviews and complaints about medications, including Zetia, may not be as reliable as other types of consumer reviews. Other side effects not listed may also occur in some patients. Here we look at how Zetia and Lipitor are alike and different. Learn more about how grapefruit may interact with medications. If you develop increased liver enzyme levels, your doctor may make changes to your treatment plan. * Sex and gender exist on spectrums. The generic form of Zetia costs about the same as the generic form of Lipitor. Its intestinal molecular target is the Niemann-Pick C1-Like 1 (NPC1L1) sterol transporter. Doing this can raise your risk of side effects. Diarrhea is a common side effect of Zetia. In fact, researchers have looked into using Zetia to treat hair loss due to a condition called alopecia areata. * This is a partial list of mild side effects from Zetia. Temporary excursions of 59F to 86F (15C to 30C) are allowed. But in studies, some people had to stop taking the drug due to feeling dizzy. Fatigue. So if youre taking Zetia with a statin drug, you may need to avoid eating grapefruit or drinking grapefruit juice during your treatment. The symptoms develop immediately and include dizziness and an intense headache. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about the change in her physical appearance. Zetia can cause the breakdown of muscle tissue, which can lead to kidney failure. Postural Tachycardia Syndrome (PoTS) is an abnormality of the autonomic nervous system (ANS). Both drugs are typically taken once each day. But some people have reported memory loss, confusion, and forgetfulness while taking a statin drug. (A drug class is a group of medications that work in a similar way.) This means you should avoid foods that are high in cholesterol and other types of fat. Healthline Media does not provide medical advice, diagnosis, or treatment. Lipitor is also FDA-approved for the following conditions when used with a low-cholesterol diet: primary dysbetalipoproteinemia in adults (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), liver complications, such as high levels of, Both Zetia and Crestor are FDA-approved to treat the following conditions* when used with a. Crestor is also FDA-approved for the following conditions in adults when used with a low-cholesterol diet: primary dysbetalipoproteinemia (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), pain on the right side of your body, below your ribs, in adults as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin drug), in adults in combination with a fenofibrate, in combination with statins, in people with hepatic disease, in combination with statins, in people with elevated hepatic transaminases, in combination with statins, during pregnancy or in someone planning to become pregnant, in combination with statins, while breastfeeding, in people who have a known allergy to Zetia. POTS is a form of "autonomic dysregulation" (a nervous system disorder) in which your heart rate spikes upon standing (among other symptoms). Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. When taken together, it should be administered at least 2 hours before or 4 hours after a bile acid sequestrant. Currently GARD aims to provide the following information for this disease: Population Estimate: This section is currently in development. Read More. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. They can give you tips on how to deal with any side effects that may be bothersome. If you think youve taken too much of this drug, call your doctor. Symptoms of a swollen gallbladder may include: Tell your doctor if you experience gallstones while using Zetia with fenofibrate. That bother you, talk with your doctor: this section is currently in development as remember. 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